Avacta Group PLC (LSE:AVCT) has shared its Q2 2025 business update, outlining key strides in its strategic initiatives, with a particular focus on advancing its clinical-stage pre|CISION® platform. The company is progressing its FAP-Dox (AVA6000) program through Phase 1b trials, demonstrating encouraging results in treating salivary gland cancers, with pivotal data anticipated in late 2025 and into 2026. Alongside clinical development, Avacta is reinforcing its leadership team by appointing new board members and a Chief Medical Officer to drive its commercial partnership goals.
The company is actively engaging with external partners to identify and pursue new commercial opportunities. Additionally, Avacta has brought on Zeus Capital as a joint broker to boost investor relations and market visibility.
While clinical advancements and strategic partnerships provide positive momentum, Avacta continues to face financial pressures and operational challenges that have affected market performance. The need for further funding remains a critical factor impacting its overall outlook.
About Avacta Group plc
Avacta Therapeutics is a clinical-stage biotechnology firm dedicated to developing targeted cancer therapies using its proprietary pre|CISION® platform. This innovative technology utilizes tumor-specific proteases to selectively activate potent treatments within the tumor environment, reducing harm to healthy cells. The company’s pipeline features peptide drug conjugates (PDC) and Affimer® drug conjugates (AffDC), which offer potential benefits over conventional antibody drug conjugates.

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