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Scancell Holdings plc (LSE:SCLP) has released positive results from its Phase 2 SCOPE trial, indicating that iSCIB1+ combined with checkpoint inhibitors could become a new benchmark for advanced melanoma treatment. The trial demonstrated a progression-free survival rate of 78% at 11 months. The company is accelerating development for iSCIB1+, including regulatory engagement and potential partnerships, with randomized studies expected to begin in 2026.

Early data from the ModiFY trial also suggests that Modi-1 improves response rates in head and neck cancer. In addition, Scancell has strengthened its executive team and secured a second commercial license with Genmab, reinforcing its strategic direction and potential for future milestones.

While the company faces significant financial challenges, with no revenue and substantial losses, recent clinical successes and strategic initiatives provide optimism for future growth. Technical indicators show mixed trends, with some short-term bullish momentum, though overbought conditions advise caution. Valuation remains unattractive due to ongoing financial pressures.

About Scancell Holdings

Scancell Holdings plc is a clinical-stage biotechnology company developing off-the-shelf active immunotherapies aimed at generating safe, durable tumor-specific immunity. Its lead product, iSCIB1+, from the DNA ImmunoBody® platform, shows promise in treating advanced melanoma. Another key therapy, Modi-1, from the Moditope® platform, is being evaluated for multiple solid tumors. The company has also launched GlyMab Therapeutics Ltd. to develop high-affinity GlyMab® antibodies targeting tumor-specific glycans.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

Brave Bison Group PLC (LSE:BBSN) posted a 19% increase in net revenue and a 6% rise in adjusted EBITDA for the first half of 2025, surpassing market expectations. The company completed five acquisitions, including the notable purchase of MiniMBA, and raised £15.5 million through a fundraising round. These strategic initiatives are expected to enhance Brave Bison’s market position and competitive reach, supporting growth prospects for FY25 and FY26.

The MiniMBA acquisition, a platform focused on marketing skills and training, will create a new practice within the company, further solidifying Brave Bison’s role as a partner for forward-looking brands.

While the company benefits from strong financial performance and a robust balance sheet, short-term technical indicators appear bearish, and moderate valuation metrics temper the outlook. Limited earnings call data and corporate developments constrain further insights.

About Brave Bison

Brave Bison is a marketing and technology partner for global brands, operating in eight countries including the UK, India, Australia, and Egypt. The company provides digital services, media, and marketing skills training through its two divisions—Digital Services and Digital Content. Its offerings include digital marketing, social and influencer campaigns, sports and entertainment, and strategic insights, serving major brands and media rights holders worldwide.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

Playtech (LSE:PTEC) delivered solid financial results for the first half of 2025, with adjusted EBITDA reaching €91.6 million, in line with upgraded guidance. The company completed the sale of Snaitech, distributing €1.8 billion to shareholders, and made significant strategic advances in core markets, particularly across the Americas.

Key developments include a revised agreement with Caliente Interactive and a transition toward a predominantly B2B business model, positioning Playtech for continued growth. While overall revenue and EBITDA declined, the company maintains a strong balance sheet with a net cash position of €77.1 million and remains on track to exceed full-year expectations. Investments in the US and Brazil are set to increase, leveraging Playtech’s market-leading technology and strategic partnerships.

The company’s outlook benefits from strong earnings performance and solid valuation metrics. However, mixed financial results, short-term bearish technical indicators, and regulatory challenges remain considerations for investors.

About Playtech

Playtech is a leading provider of platforms, content, and services for the online gambling sector. The company delivers innovative solutions for gaming operators and maintains a strong presence in both B2B and B2C markets, with a focus on regulated jurisdictions in Europe and the Americas.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

Lords Group Trading PLC (LSE:LORD) recorded an 8.4% increase in group revenue for the first half of 2025, led by strong performance in its merchanting division. The company expanded its operations by acquiring Construction Materials Online and opening three new branches, further strengthening its market presence. Despite ongoing challenges in the RMI sector, management remains positive about future growth prospects, supported by a fortified balance sheet and targeted strategic initiatives.

The company’s outlook reflects solid corporate developments and resilient financial performance despite market pressures. Technical analysis, however, shows bearish momentum, and the negative earnings contribute to an unattractive valuation, tempering overall investor sentiment.

About Lords Group Trading PLC

Lords Group Trading PLC is a major UK distributor of building materials, serving primarily the merchanting and plumbing & heating sectors. The company focuses on expanding market share through strategic acquisitions and operational excellence, aiming to maintain a leading position in its industry.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

Rockfire Resources PLC (LSE:ROCK) has commenced diamond drilling at its Molaoi zinc deposit in Greece, starting on September 15, 2025. The program aims to upgrade the resource classification from JORC Inferred to Indicated and to define a maiden germanium Inferred resource.

The drilling plan includes 30 holes, each ranging from 200 to 450 meters in depth, totaling roughly 10,000 meters. Results will be published as they are received, with operations expected to continue until at least February 2026. This initiative represents a major step in expanding Rockfire’s resource base and enhancing its position in the market.

About Rockfire Resources PLC

Rockfire Resources PLC is an exploration company focused on base metals, critical minerals, and precious metals. Its primary project is the 100%-owned Molaoi zinc deposit in Greece, which the company is actively developing.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

Trifast plc (LSE:TRI) has reported that its trading performance for the first four months of FY2026 is in line with expectations. The company credited margin recovery and the execution of its ‘Recover, Rebuild, Resilience’ strategy for maintaining stability. Despite macroeconomic pressures impacting some industrial sectors, Trifast’s global manufacturing footprint and engineering capabilities have helped sustain resilience.

Looking ahead, the company remains confident in achieving its medium-term targets, including an EBIT margin exceeding 10%, while anticipating ongoing growth and enhanced cash generation.

Trifast’s outlook is supported by operational efficiency improvements and positive technical momentum, alongside insider confidence demonstrated through share purchases. However, challenges persist in revenue growth and cash flow, and a high price-to-earnings ratio raises valuation considerations.

About Trifast

Trifast plc is a global specialist in the design, engineering, manufacture, and distribution of precision-engineered fastenings and Category ‘C’ components. Serving major international assembly industries such as Automotive, Smart Infrastructure, and Medical Equipment, the company provides end-to-end support from concept design through to global logistics. Its operations span the UK & Ireland, Asia, Europe, and North America, with manufacturing facilities focused on high-volume cold-forged fasteners and specialized components.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

Zenova Group PLC (LSE:ZED) has signed a non-binding agreement to acquire Restoreo International Limited, a move that could significantly reshape the company’s scale and business focus. The transaction, structured as a reverse takeover, is intended to merge Zenova’s fire safety and insulation technologies with Restoreo’s distribution capabilities, creating a global platform for expansion.

The deal is expected to strengthen Zenova’s energy efficiency offerings, though it remains subject to regulatory approvals and shareholder consent. Meanwhile, trading of Zenova shares on AIM has been suspended pending further announcements.

About Zenova Group PLC

Zenova Group PLC develops and supplies advanced fire safety and temperature management solutions across industrial, commercial, and residential markets. Its portfolio includes fire protection paints, thermal insulation coatings and renders, fire extinguishers, aerosol fire suppression systems, automatic ceiling sprinklers, and wildfire barriers, all designed to meet stringent safety and efficiency standards.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

Aptamer Group plc (LSE:APTA) has entered into a new agreement with Metir plc to develop Optimer® binders for the rapid identification of Cryptosporidium within Metir’s Pathogen Detector platform. The collaboration is designed to improve real-time water quality monitoring and represents a step forward in pathogen detection capabilities.

The partnership highlights the versatility of Aptamer’s technology and its potential to move into wider markets. Proof-of-concept results are expected in the near term, which could pave the way for pilot trials by UK water utilities.

Aptamer Group’s outlook remains constrained by ongoing financial pressures and weak technical signals. Nevertheless, the company’s strategic partnerships and pipeline of corporate developments provide some optimism for longer-term growth. Heavy debt levels and continued unprofitability, however, remain key risks.

About Aptamer Group

Aptamer Group plc operates within the life sciences sector and focuses on creating next-generation synthetic binders. Its flagship Optimer® products are engineered for pathogen detection and environmental monitoring, offering high stability and specificity across applications.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

Centaur Media (LSE:CAU) has agreed to sell its legal information platform, The Lawyer, to Lighthouse Bidco Limited for £43 million. The move follows a broader strategic review aimed at unlocking shareholder value, coming shortly after the disposal of its MiniMBA business. Management said the sale will provide significant cash proceeds, with plans to consult investors on a potential capital return. Completion of the transaction is expected in early October.

Post-sale, Centaur intends to concentrate on its core marketing brands, aligning the business more closely with its long-term strategic objectives.

The company’s outlook is currently underpinned by favorable corporate developments and stable technical trends. However, pressure on revenues and profitability remains a concern. Valuation signals are mixed, with a negative price-to-earnings ratio offset by an attractive dividend yield.

About Centaur Media

Centaur Media is an international provider of specialist business information, training, and consultancy services, with a focus on the marketing and legal industries. Its mission is to inspire and support clients in achieving excellence, raising ambitions, and driving improved performance.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

LondonMetric Property Plc (LSE:LMP) has completed £78.5 million in triple net lease (NNN) acquisitions across five separate deals. The newly added assets—which include Premier Inn hotels, logistics warehouses, and convenience properties—are expected to deliver £4.6 million in annual rental income. Over the next five years, the portfolio is forecast to lift its net initial yield (NIY) from 5.5% to 6.3%.

These investments expand LondonMetric’s footprint in the budget hotel segment while reinforcing its exposure to high-demand areas such as logistics and convenience retail. The company noted that the acquisitions enhance asset diversity and align with evolving consumer preferences around experience, entertainment, and convenience. Management anticipates similar opportunities in the future as part of its ongoing strategy.

LondonMetric’s investment case is supported by strong revenue and earnings growth, an attractive valuation, and a compelling dividend yield. Still, technical signals currently suggest a short-term bearish outlook, tempering some of the optimism around the stock’s performance.

About LondonMetric Property

LondonMetric Property Plc is a leading UK-based real estate investment trust (REIT) specializing in triple net lease properties. With a portfolio valued at approximately £7 billion, the company focuses on sectors such as logistics, convenience, healthcare, entertainment, and leisure. Its strategy is centered on owning and managing properties that meet tenant demand, generating predictable and growing income streams, and delivering long-term outperformance.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.