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Oxford BioDynamics (LSE:OBD) has introduced a pioneering blood test capable of diagnosing Chronic Fatigue Syndrome (CFS) with an impressive 96% accuracy rate. This innovation represents a major leap forward in providing a dependable diagnostic option for a condition that affects millions worldwide and has long eluded clear medical understanding. Developed using the company’s proprietary EpiSwitch® 3D genomics platform, the new test not only enhances diagnostic precision and patient management for CFS but could also serve as a foundation for future tests targeting related conditions such as long Covid—strengthening Oxford BioDynamics’ foothold in the precision diagnostics market.

Despite this scientific milestone, the company faces ongoing financial headwinds. Persistent net losses, negative cash flows, and weak valuation metrics, including a negative price-to-earnings ratio, weigh heavily on its market outlook. Technical indicators remain mixed, reflecting investor caution about near-term performance.

About Oxford BioDynamics

Oxford BioDynamics Plc is a global biotechnology firm dedicated to advancing personalized medicine through precision clinical diagnostics. Its portfolio includes the EpiSwitch® PSE test, designed to improve the accuracy of prostate cancer detection, and the EpiSwitch® CiRT test, which helps predict patient responses to immuno-oncology therapies. Leveraging its proprietary 3D genomic biomarker platform, EpiSwitch®, the company continues to expand its diagnostic applications across diverse medical areas such as oncology, neurology, and inflammatory diseases.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

Gold futures surged to an all-time high on Tuesday, briefly surpassing the $4,000-per-ounce mark as investors flocked to safe-haven assets amid escalating political and economic uncertainty worldwide and growing expectations of additional U.S. interest rate cuts.

By 10:02 ET (14:02 GMT), gold futures were up 0.6% at $3,999.85 per troy ounce, while spot gold advanced 0.5% to $3,979.88 per ounce.

The metal’s latest rally has been supported by mounting political turmoil in major economies, including the U.S., France, and Japan. An ongoing U.S. government shutdown and renewed speculation about a Federal Reserve rate cut later this month have strengthened gold’s traditional role as a store of value during periods of instability.

Markets now widely expect the Fed to cut rates by 25 basis points at its October 28–29 meeting, according to CME’s FedWatch Tool. The central bank already restarted an easing cycle in September and signaled that further reductions could follow before year-end — a backdrop that favors non-yielding assets like gold.

Despite the government shutdown, some Fed-related data will still be released today, including the New York Fed’s consumer expectations survey. Several Fed officials are also scheduled to speak, though analysts say the lack of fresh data may limit the impact of their remarks on rate expectations.

Further support came from China, where the People’s Bank of China (PBOC) extended its gold-buying streak into an 11th consecutive month. The central bank’s holdings rose to 74.06 million fine troy ounces at the end of September, up from 74.02 million in August. The value of its gold reserves also climbed sharply, reflecting the rally in prices.

China’s continued purchases are viewed as part of a broader effort to diversify its foreign reserves away from the U.S. dollar and Treasuries, amid deteriorating relations with Washington.

Political unrest lifts gold further

According to analysts at ING, “political shakeups in France and Japan […] fueling fiscal concerns” have further underpinned gold prices, alongside “a surge in demand from both retail investors and institutional inflows in Europe and Japan.”

In France, political tensions have escalated following the unexpected resignation of Prime Minister Sébastien Lecornu. President Emmanuel Macron has asked Lecornu to continue talks with political parties in hopes of building a new governing majority, though his role during negotiations remains unclear. There is growing speculation that France may hold a snap parliamentary election, with both far-right and far-left parties pushing for change.

In Japan, Sanae Takaichi, a fiscal dove, was elected as the new leader of the ruling Liberal Democratic Party, setting her up to become Japan’s first female prime minister. The yen weakened sharply following her victory, while Japanese government bond prices declined on doubts over how she plans to finance her agenda of stimulus spending and tax cuts.

The global wave of political uncertainty has kept investors anchored to gold, driving the precious metal to fresh records. Silver and platinum have also posted decade highs in recent sessions.

Meanwhile, copper prices edged higher after Freeport-McMoRan (NYSE:FCX) provided no timeline for restarting operations at its Grasberg mine in Indonesia, one of the world’s largest copper producers, following a fatal accident in early September that halted output.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

Shares of Tesco (LSE:TSCO) and J Sainsbury (LSE:SBRY) moved lower on Tuesday after Asda announced another round of price reductions across its stores, intensifying competition in the UK supermarket sector.

Following the announcement, Tesco shares fell roughly 0.6%, while Sainsbury’s declined around 1%, as investors weighed the potential impact on margins and pricing strategies across the industry.

Asda said it had cut prices by an average of 6% across a wide range of categories, including staple groceries, household essentials, and non-food products, with some individual items seeing reductions exceeding 30%.

The retailer added that the initiative covers multiple store departments, emphasizing key everyday goods most frequently purchased by customers, as part of its strategy to strengthen its value positioning amid persistent cost-of-living pressures in the UK.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

UK equities traded slightly higher on Tuesday, supported by gains in Shell and Imperial Brands, while B&M European Value Retail tumbled after posting disappointing results and cutting its earnings guidance.

By 13:22 GMT, the FTSE 100 was up 0.2%, while the British pound slipped 0.5% against the dollar, hovering just above $1.34. On the continent, the DAX in Germany and CAC 40 in France each advanced 0.2%.

Supermarket stocks weighed on the index after Asda announced a broad round of price cuts. Tesco (LSE:TSCO) shares dropped 0.6% and J Sainsbury (LSE:SBRY) declined 1% following the news. Asda said it had reduced prices by an average of 6% across groceries, household items, and non-food categories, with some goods seeing cuts of over 30%.

Shell (LSE:SHEL) rose after releasing its third-quarter trading update, which showed stronger performance across several business units. The company reported improved liquefaction volumes, higher trading activity, and better refining margins. Analysts at Jefferies described the report as “overall a positive update”, suggesting potential 5–10% upside to consensus earnings of $4.57 billion. The improvement was largely attributed to Shell’s integrated gas and products segments, which both benefited from favorable market conditions.

Imperial Brands (LSE:IMB) also advanced after reaffirming that it remains on track to meet its FY25 guidance. The tobacco maker expects low single-digit growth in net revenues from both its traditional tobacco products and next-generation products (NGP), supported by strong pricing and double-digit NGP expansion. The group anticipates high single-digit EPS growth at constant currency, driven by profit gains and ongoing share buybacks.

In contrast, B&M (LSE:BME) shares plummeted more than 15% after the discount retailer reported a drop in first-half profit, trimmed its full-year earnings outlook, and unveiled a turnaround strategy to stabilize UK operations. Revenue for the first half of fiscal 2026 rose 4% year-over-year to £2.75 billion, but profitability fell short of expectations.

CVS Group (LSE:CVSG) surged over 10% after the veterinary services provider posted FY25 adjusted EBITDA of £134.6 million, slightly ahead of forecasts. Like-for-like sales rose 0.2%, below the company’s 4%–8% target, while adjusted EPS declined 3.8% to 80.1p due to higher costs.

In the automotive sector, Jaguar Land Rover (JLR) said it will resume production on Wednesday after a cyber incident that disrupted operations since early September. The phased restart will begin at its Electric Propulsion Manufacturing Centre and Battery Assembly Centre in the West Midlands, with employees returning to stamping operations and vehicle production at Castle Bromwich, Halewood, and Solihull.

Meanwhile, in the housing market, UK home prices slipped 0.3% in September to an average of £298,184 ($401,010), according to Halifax. It marked the first monthly decline since May, suggesting that concerns over potential tax increases may be starting to weigh on buyer demand.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

U.S. stock index futures were little changed early Tuesday, suggesting a muted open on Wall Street as investors digested the latest political and market developments following Monday’s gains.

Traders appeared hesitant to take bold positions while monitoring the ongoing budget impasse in Washington, where lawmakers once again failed to approve a temporary spending bill overnight.

Although markets have so far brushed off the effects of the government shutdown, the absence of key U.S. economic data releases could keep some investors on the sidelines this week.

Attention is also turning to comments from Federal Reserve officials, as market participants look for clues about the future path of interest rates following recent policy signals.

On Monday, the major U.S. indices mostly advanced, extending last week’s momentum. The Nasdaq Composite jumped 161.81 points, or 0.7%, to 22,941.67, while the S&P 500 gained 24.49 points, or 0.4%, to 6,740.28. The Dow Jones Industrial Average, however, slipped 63.31 points, or 0.1%, to 46,694.97.

Gains were led by semiconductor stocks, with the Philadelphia Semiconductor Index climbing 2.9% to a record close. Advanced Micro Devices (NASDAQ:AMD) surged 23.7% after announcing a 6-gigawatt deal to power OpenAI’s next-generation AI infrastructure using its Instinct GPU lineup.

As part of the partnership, AMD granted OpenAI a warrant for up to 160 million shares of AMD stock, structured to vest once specific milestones are achieved.

Meanwhile, gold miners rallied, tracking a sharp increase in gold prices, as the NYSE Arca Gold Bugs Index rose 1.9%. Software stocks also posted notable gains, while housing and commercial real estate shares moved lower.

Despite the political uncertainty, market sentiment remained resilient, with most traders continuing to discount the potential economic fallout from the ongoing shutdown.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

European equity markets traded slightly weaker on Tuesday, pressured by mounting political uncertainty in France and disappointing factory order data from Germany.

The latest government reshuffle in France sent ripples through European bond markets, pushing the German 10-year bund yield—the eurozone’s key benchmark—up 1.4 basis points to 2.73%.

Fresh data from Destatis showed that German factory orders dropped 0.8% in August, following a 2.7% decline in July, defying expectations for a 1.2% rebound. Excluding major bulk orders, new orders were down 3.3% month-over-month, underscoring persistent weakness in Europe’s largest industrial economy.

By mid-morning, the DAX Index in Germany was up 0.2%, while France’s CAC 40 and the UK’s FTSE 100 both gained 0.3%, signaling limited momentum across the region.

Sector-wise, healthcare stocks underperformed, with Germany’s Bayer (TG:BAYN) plunging 4% and Denmark’s Novo Nordisk (NYSE:NVO) sliding 2%.

In contrast, energy shares provided some support. Shell (LSE:SHEL) climbed nearly 2% in London after issuing an upbeat third-quarter 2025 outlook, while Imperial Brands (LSE:IMB) advanced 3% following the announcement of a £1.45 billion ($1.95 billion) share buyback.

Among other notable movers, Skanska (USOTC:SKBSY) jumped 4.5% and wind turbine maker Nordex (BIT:1NDX) rose 1% after securing new contract wins.

Meanwhile, Great Portland Estates (LSE:GPE) slipped 1% despite reporting strong leasing activity during the first half of its fiscal year, and discount retailer B&M European Value Retail (LSE:BME) dropped 10% following a profit warning.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

Wizz Air (LSE:WIZZ) plans to have its entire Airbus (EU:AIR) fleet back in service by the end of 2027, as the airline continues to grapple with ongoing engine-related groundings, according to Chief Financial Officer Ian Malin, who spoke on Tuesday.

During the International Society of Transport Aircraft Trading (ISTAT) conference in Prague, Malin said that 38 aircraft remain grounded due to lengthy inspection delays, down from a peak of nearly 60. This marks a modest improvement compared with the 41 aircraft grounded at midyear as a result of Pratt & Whitney (NYSE:RTX) GTF engine inspections.

“Overall, the plan right now is to get the entire fleet unparked by the end of calendar year 2027. That is the target that we’re working towards,” Malin stated at the conference.

The CFO cautioned, however, that achieving this goal will not be easy, saying: “That will be challenging, especially when we’re sitting here with 38 aircraft on the ground.”

Malin also noted that supply chain bottlenecks at Pratt & Whitney persist, with no visible improvement yet, continuing to hinder the airline’s efforts to return grounded jets to operation.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

France has lowered its 2025 wine production estimate to 36.0 million hectolitres, down from the 37.4 million hectolitres forecast a month earlier, the French Agriculture Ministry said on Tuesday.

The revised outlook marks a 1% decline compared to last year’s harvest and is 16% below the five-year average, reflecting the continued challenges facing the country’s vineyards.

Officials attributed the downgrade primarily to the severe heatwave that struck in August, which affected grape yields and quality in several key wine-producing regions. The new estimate is based on updated harvest data collected nationwide, incorporating the latest reports from growers and regional cooperatives.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

Renault Group (EU:RNO) expects its third-quarter retail sales to rise by a high single-digit percentage year-on-year, with September performance matching July–August growth of 9%, according to Investor Relations head Florent Chaix, speaking during a preview call ahead of the company’s October 23 revenue announcement.

The Dacia brand continues to outperform, supported by robust demand for the Bigster, which has accumulated 50,000 orders and now ranks as the second-best-selling C-segment SUV in Europe. Over 80% of Bigster orders are for high-trim versions, and more than half are hybrid models. Meanwhile, the Renault 5 remains the leader in the B-segment EV market, while production of the Renault 4 is set to ramp up in the fourth quarter.

Geographically, Germany, Spain, and the UK are leading growth in passenger car sales, while Italy remains weaker. Dacia continues to outperform across the EU, with additional momentum in Turkey, Romania, and Argentina.

Despite these solid retail trends, a greater destocking of independent dealers compared with Q3 2024 (down 72,000 units) will temporarily weigh on volume figures. However, Renault still expects positive volume contributions in both Q3 and Q4, supported by healthy inventories and a year-over-year increase in orders.

The company projects a foreign exchange headwind of over 1% for Q3 — a greater impact than in the first half of the year. The product mix remains favorable but less pronounced, while the geographic mix is slightly positive. The European market remains competitive, resulting in modestly negative pricing.

Sales to partners continue to perform well, and the “Other” segment should remain slightly positive, albeit well below last year’s 5-point contribution. Financial services are maintaining strong double-digit growth, in line with the first half, and mobility services have more than doubled.

Looking ahead, Renault anticipates a robust fourth quarter, underpinned by its strong order book and new model launches, with no plans to pursue discount-driven sales. The company has moderated some Q3 production, while keeping high utilization rates. Renault reaffirmed its operating margin target of 6.5% and expects positive working capital in H2, although it remains negative for the full year.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.

 Shares of Ocado Group Plc (LSE:OCDO) dropped on Tuesday after Morgan Stanley lowered its price target by 19% to 170p from 210p, while maintaining an “underweight” rating on the stock. The investment bank warned of “increased execution risk” in the company’s automated warehouse operations, citing rising uncertainty around its U.S. partnership with Kroger (NYSE:KR).

In a bearish note, the brokerage said that recent developments suggest Kroger “is pivoting toward the use of food delivery aggregators, namely Instacart, to service demand in a more asset-light fashion, focusing on sub-one-hour delivery.” The shift could reduce Kroger’s reliance on Ocado’s large-scale customer fulfilment centres (CFCs).

Morgan Stanley now expects two CFC closures in fiscal 2026, potentially in Florida and Maryland, and forecasts that the remaining facilities will have shorter operating lives of about 15 years, compared with 30 years in previous assumptions. As a result, the bank cut the number of CFCs in Ocado’s valuation model from 36 to 30, assigning each a net present value of £54 million.

The report estimates that Ocado could receive £17 million in exit fees per closed CFC, or roughly £34 million in additional revenue in 2026. However, it projects a 5% decline in total group revenue in 2027, along with an 8% year-on-year fall in adjusted EBITDA.

Morgan Stanley forecasts group revenue to reach £1.34 billion in 2025, rising to £1.45 billion in 2026, and £1.51 billion in 2027. Adjusted EBITDA is expected to grow from £177 million in 2025 to £253 million in 2026, before easing to £280 million the following year. Meanwhile, net debt is projected to widen from £1.43 billion in 2024 to £1.63 billion in 2025.

The bank also anticipates that Ocado will remain free cash flow negative until 2029, lagging behind the company’s own projection of breaking even in the second half of 2026.

Morgan Stanley added that “the value and payback period of each CFC for Ocado and its customers remains unclear,” and that “we see increased execution risk on the CFC pipeline over the long term.”

In its risk-reward analysis, the bank set a bull case of 610p per share, assuming faster contract wins and stronger profitability, and a bear case of 100p, reflecting the absence of new deals and possible client exits. The base case valuation of 170p implies an enterprise value of £2.47 billion, including £1.62 billion attributed to Ocado’s Solutions division, £370 million to logistics, and £391 million to its retail joint venture with Marks & Spencer.

Ocado shares closed at 232p on October 3, within a 52-week range of 411p to 217p, giving the company a market capitalization of £1.9 billion.

The downgrade follows previous Morgan Stanley assessments that described Ocado’s business model as “still unproven”, citing limited visibility into long-term profitability.

This content is for informational purposes only and does not constitute financial, investment, or other professional advice. It should not be considered a recommendation to buy or sell any securities or financial instruments. All investments involve risk, including the potential loss of principal. Past performance is not indicative of future results. You should conduct your own research and consult with a qualified financial advisor before making any investment decisions.